Kill the Countess in the tower under the Black Marsh. Over, and over, and over, and over, and over.She can't drop the very highest runes, but she can drop some pretty awesome ones. For the highest runes, you'll want to kill Baal. His rune drop rate is much lower, but it's still your best bet.When first killing Countess on Hell, the highest rune that can drop is Lo. Every time after that, the highest rune she can drop is Ist. She'll pretty much drop runes every time you kill her (very low chance of getting no runes). Baal on the other hand can drop all of the highest runes, including Zod (which I believe is a rune that can only be dropped in Act 5 Hell).
I found that the way of making game T6 with lvl 1 char and then open rift with it / invite lvl 70 firiend ( and boom! You are lvling super fast 'stay alive' some distance from your friend clearing the rift for you. ) about 30+ lvl first rift. Every rift it gets slower because monsters gets stronger every lvl. While leveling in Diablo II it is important to remember that until you get a character to level 25 it is best to try and only kill monsters that are within three levels of yours. For example, if your character is at level 10, try and stick to killing monsters that are in the 7 to 13 range( reference ).
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From 's comment. The monster with the highest probability of dropping runes is the countess in Act 1 (Forgotten Tower). I think she even drops at least one rune every time.
AFAIK Andariel and Nilathak also have a rather high chance of dropping a rune, but not even close to the Countess. Chaos guide total war warhammer 2. Nilathak can drop much higher runes though.might be helpful.As for gems: Just go to areas with lots of monsters (cow level might be good) and collect all gems for transmuting.Another option to farm runes and gems would be to do hellforge rushes. That's only viable online though where you can rush a lot of people at the same time and share the drops. Countess is great place only for mid range runes. Ist rune is very very low chance.If you want to farm high runes(Ist and up) running Countess IS NOT a good place to do so.Kiling lots of monsters on hell with /players 7 is the best way to do it. Speed of killing is the best thing you'd be looking at, so you should lower /players x until you reach fast killing.Dense zones with monsters and elites should be your first choice, e.g. Cows, council members, even act 1 fallen camps.Alternative but boring way is opening chests in lower Kurast on players 8.
You can google/youtube how to do it.
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Blizzard Software's PC and Mac game, Diablo II, has a huge and loyal fan base that continue to play the game faithfully years after its 2000 release. A thriving market has sprung up for Diablo II items, in which users can pay real-world currency for weapons, armor and magical items. However, you don't need to hand over real cash for in-game items. There's a secret level loaded with bonus items and loot, and a couple of tricks to double your most valuable items for added battling power or financial reward. From your Stash treasure chest, retrieve your Horadric Cube (which you received for completing the 'Halls of the Dead' quest) and Wirt's Leg (gained by searching Wirt's body during the 'Search for Cain' quest).Place the Tome of Town Portal and Wirt's Leg into the Horadric Cube to transmute them. A portal will appear to a secret bonus level simply called the 'Cow Level.' Defeat the attacking Cows, but do not kill the halberd-wielding Cow King.
While the King remains alive, you can travel to this level as many times as you desire, gathering money and bonus items, then escaping through the portal.Item Duplication (Single-Player)Travel to an area populated with monsters.Drop an item that you wish to duplicate, or wait until a monster drops one.Activate a Town Portal near the item, then position your character so that the portal is between you and the item.Left-click on the item to pick it up. Your character will step into the portal before she can pick up the item, but when you emerge from the portal, the item will be in your Inventory.Return through the portal to pick up the original item. You now have two of the same items, one of which can be sold or kept as a spare.Item Duplication (Multi-Player)Fill your Quickslots with health and mana potions and go to an area free from monsters. Any Town Square will work.Drop the item you wish to duplicate and walk a few steps away from it.Left-click on the item to walk to it.Move one of your Quickslotted potions into the play area by left-clicking and dragging with the mouse. Do not drop the potion yet.Release the mouse button to drop the potion once your character has picked up the item. If you have timed it right, the potion will turn into a duplicate of your item, which you can now sell or trade with another player.